Melanotan II is an unlicensed and largely untested form of alpha-melanocyte-stimulating hormone, which causes pigmentation (tanning) of human skin. Melanotan II is a variant of melanotan I (afamelanotide), a drug used in the treatment of erythropoietic protoporphyria.

Melanotan II Peptide Pre Mixed Pen

  • Manufactured by: hygehgh Biopharm Co., Ltd.
  • Country of origin: China
  • Manufactured since: 2010 – Present
  • Package :2mg/10vials/kits ,10 mg / 3 ml/pen
  • Price: $1.3 – $3 per IU
  • Minimum Order:1 kits
  • Storage:2–8 ℃ in (room temperature)
  • Delivery: 5-15 days
  • Source: tophygetropin.com/shop/

Melanotan II benefit & effect

  • Lasting Tan: Even if the dosage is stopped, a warm sun-kissed tan can last for months at a time without any exposure to the sun. Conversely, tans developed naturally fade in around a months time.
  • Flexibility of Use: Able to take a small loading dose with continued dosing until desired skin pigmentation is achieved. Once achieved only need to dose once every couple of weeks to maintain the same pigment.
  • Reduced exposure to sunlight (UV rays): Melanotan still needs exposure to sunlight to be effective. However, it will allow the user a significant reduction in time to develop the desired tan.

How does melanotan II work?

Melanotan II non-selectively mimics the action of melanocortin peptides. These are natural hormones involved with pigmentation, energy homeostasis, sexual functioning, the immune system, inflammation, and the cardiovascular system. Much like melanotan I (afamelanotide), melanotan II stimulates the production of eumelanin, causing the skin to go darker (tanning).

Melanotan II is usually administered as an injection of liquid underneath the skin, commonly every second day. Trials have shown that the tanning effect can occur within 5 doses.

Melanotan II ide effect and Some Clinical phenomenon

Short term side effects after administration include:

Facial flushing
Reduced appetite, nausea and vomiting
In males, spontaneous erections 1-5 hours after administration (priapism), associated with yawning and stretching complex


Long term, there is concern that melanotan II may increase the risk of:

Melanoma – a potentially serious form of skin cancer
Deepening of the colour of moles, new moles and atypical melanocytic naevi
Melanonychia – brown to black discolouration of one or more nails
Rhabdomyolysis – potentially fatal destruction of muscle cells
Encephalopathy syndrome
There is also concern about possible side effects due to contamination or lack of sterility if melanotan II is prepared incorrectly or needles are shared.

Sexual dysfunction


During clinic trials for its use as a tanning agent, melanotan II was found to be a potent stimulator of male erections. A new drug based on melanotan II, bremelanotide, was developed to take advantage of this property. It has been noted across several studies to increase rigidity and duration of male erection, as well as male sexual desire. It has also been shown to increase female sexual desire in patients with sexual arousal disorder.

How To Use The Melanotan II ?

helpful reference Melanotan II dosage calculator

Noteworthy: Many online sources sell an ineffective product. Also, peptides are fragile by nature and are not effective when they are taken orally (pills, shakes, etc) because they will be broken down by the digestive process. Instead, peptides are mixed with bacteriostatic water and then injected under the skin with an insulin needle. Peptide injections or injectable melanin in this manner are nearly painless and have clinically proven effectiveness.

Conclusions: Melanotan not a treatment or cure for anything. Nor should it be considered a preventative treatment for skin cancer. Despite this tanning peptide being known to protect the skin through the natural tanning process, it is not in and itself a guaranteed full proof UV shield. However, it is a great way for those who don’t tan easily to get sun-kissed all year long with minimal exposure to the sun.

How to Mix Melanotan II ?

before using Melanotan II, follow these instructions:

  • Add 1mL of sterile water to the Melanotan II vial.
  • Release the water slowly and strictly on the side of the glass vial.
  • DON’T SHAKE the vial violently as this will disrupt the solution.
  • Continue to swirl until all the powder dissolves to achieve a clear solution.
  • For the blue top Per mix AQ,put in the injection pen.

How does it work?

Melanotan 2 works by stimulating the release of the pigment melanin from the skin. Less UV exposure is necessary with Melanotan 2 compared to “normal tanning”, and the tan that occurs with tanning injections is deeper and longer lasting than an individual’s “normal tan”. Melanotan works best (has the most noticeable effects) on people with fair skin tones.

Injection Sites :Where To Injection The Melanotan II ?

The peptide is shipped enclosed in a vial. It is in a powder dried form that must be reconstituted using sterile water and then injected under the skin (subcutaneously) where it is absorbed into the skin and spread throughout. Or ask your bodybuilding coach or doctor.

Storage Of Melanotan II

Before dilution, keep getropin hgh at 2-8 °C (room temperature) and avoid cold storage.

Length of use

Melanotan II results are not produce immediately. It might take 2 to 3 months before you can see results. Melanotan II cycle is after every 6 months.

Melanotan II Mixed reviews Summary

Don’t be surprised. A lot of people haven’t heard of Melanotan. Melanotan is a tanning peptide that stimulates the production of melanin in the body to foster a deep, natural tan. This is the body’s way of protecting itself from too much sun exposure by increasing the level of melanin in the body. Melanin is your body’s natural response to UV damage. The end result is a darkening of the skin.

Obviously, the drawback from too much tanning is the amount of damage UV radiation can do. This can lead to skin cancer and other serious health problems.
Melanotan not a treatment or cure for anything. Nor should it be considered a preventative treatment for skin cancer. Despite this tanning peptide being known to protect the skin through the natural tanning process, it is not in and itself a guaranteed full proof UV shield. However, it is a great way for those who don’t tan easily to get sun-kissed all year long with minimal exposure to the sun

Melanotan II review

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