DSIP, also known as delta sleep-inducing peptide (DSIP),DSIP is a nonapeptide that is synthesized in a few parts of the brain: the hypothalamus, pituitary, and adrenal glands. It can pass through the blood-brain barrier, which is unusual when compared to other peptides. As the name suggests, DSIP has a sleep-activating function due to its ability to induce slow-wave sleep on animals.

DSIP Pre Mixed Peptide pen

  • Manufactured by: HygHGH Biopharm Co., Ltd.
  • Country of origin: China
  • Manufactured since: 2009 – Present
  • Package :10mg /3ml /1 pen box
  • Purity:99%
  • Price: $1.3 – $3 per IU
  • Minimum Order:1 kits
  • Storage:2–8 ℃ in (room temperature)
  • Delivery: 5-15 days
  • Source: tophygetropin.com/shop/

The discovery of DSIP was initiated through a clinical study observed on rabbits. In 1974, a group of Swiss scientists isolated DSIP from the cerebral venous blood of rabbits in an induced state of sleep. This finding was only the beginning. For over four decades of research, several more physiological effects were uncovered, which associate DSIP with positive benefits not only on animals but humans as well.

Studies have also shown that DSIP has exhibited a stress-protective action that helps decrease stress metabolic disorders for humans and animals.

It is believed that the Delta Sleep-Inducing Peptide works in such a way that it modulates the activity of GABAergic gluta and other neuronal systems too.

DSIP Peptide benefit & effect

1. Regulates Sleep Patterns


The most substantial benefit of DSIP is its influence on the regulation of sleeping patterns for humans. After the initial discovery of this peptide, more studies followed only to test the given hypothesis: “that DSIP may be the principal endogenous sleep factor.” Additional reports came out about an increase in the sleep-prompting effect on human subjects injected with small doses. Other studies also found out its ability to induce delta-wave sleep. They led to future examinations on DSIP, specifically on the possibility that it could be an effective treatment for insomnia.

It is important to note that DSIP is not advisable to be used as an alternative to sedatives. Also, the results that yielded positive effects of DSIP involved subjects who were suffering from sleep disturbance. Healthy subjects who did not have complaints regarding a disrupted circadian rhythm yielded minimal significant results. Although, a full restoration on the circadian rhythm is still bound for more in-depth clinical research.

2. Regulates Secretion of ACTH and LH Hormones


DSIP is also associated with the secretion of Adrenocorticotropic Hormone (ACTH). With a healthy circadian rhythm, ACTH follows the protocol of being at a high level in the morning (normal level), a gradual decrease during the day, and reaches the lowest level during the night. Some studies showed that DSIP significantly decreased ACTH levels, thus promoting the sleeping state of the body.

This peptide also stimulates the release of Luteinizing Hormone (LH) levels. This regulation helps in the inhibition of somatostatin, a growth hormone-inhibiting hormone (GHIH).

3. Analgesic For Chronic Pain


DSIP peptide has other unrelated properties that may be beneficial for chronic pain relief. For example, some studies show that it affects the reduction of amphetamine-induced hyperthermia.

“The agent has been used for the treatment of alcohol and opioid withdrawal with some success. Clinical symptoms and signs disappear after injection of DSIP, although some patients have reported occasional headaches. (Pollard & Pomfrett, 2001)”

4. Normalizes Blood Pressure


Moreover, DSIP also elicits antihypertensive effects.

A study on spontaneously hypertensive rats (SHR) measured that within ten days of DSIP infusion, it resulted in the maintenance of blood pressure at a certain level.

DSIP Peptide Peptide side effect

There are possible side effects on short-term or long-term use of DSIP peptides. However, no significant side-effects have so far been reported with the use of DSIP, whether on animals or humans. Nonetheless, It is recommendable to consult your doctor before taking any peptide products.

How DSIP Peptide works?

There are possible side effects on short-term or long-term use of DSIP peptides. However, no significant side-effects have so far been reported with the use of DSIP, whether on animals or humans. Nonetheless, It is recommendable to consult your doctor before taking any peptide products.

Interestingly, DSIP injection boosts the survival rate of animals under emotional stress and balances various physiological parameters. The way DSIP works is through the activation, or switching on, of the serotonergic system of the brain. Then, DSIP increases the activity of monoamine oxidase A (MAO-A) – using serotonin as a substrate – in the mitochondria (the powerhouse of the cell). DSIP can cross the blood brain barrier and also can be absorbed by the human gut with being broken down by gut enzymes.

Dosage of The DSIP Peptide

ask your doctory.


Disclaimer: The DSIP Peptide currently listed on this site is sold for research use only. Not for human consumption. This product is not a drug, supplement, food or cosmetic and it may not be misused, sold, labeled or branded as such.

How to Mix DSIP Peptide?

before using the BPC-157 Peptide , follow these instructions:

  • Add 1mL of sterile water to the Dsip Peptide vial.
  • Release the water slowly and strictly on the side of the glass vial.
  • DON’T SHAKE the vial violently as this will disrupt the solution.
  • Continue to swirl until all the powder dissolves to achieve a clear solution.
  • For the Dsip peptide pre mixed,Use it directly.

Storage Of The DSIP Peptide

Minimize open air exposure, store in a cool dry place.

The DSIP Peptide Mixed reviews Summary

Indeed, DSIP can:

  • Help induce better sleep
  • And relieve emotional and psychological responses to stress

Although, it is not recommended to give out DSIP just before going to bed. The dose should be given during the day to help improve sleep the next night and as well as several days to come.

 But you must remember that DSIP only works for short-term benefits and not for long-term management for insomnia. 

Now that you know all about it, it’s time to give you a good night’s rest.

DSIP Peptide review

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